DNA-binding proteins are proteins that are composed of DNA-binding domains and thus have a specific or general affinity for either single or double stranded DNA. Sequence-specific DNA-binding proteins generally interact with the major groove of B-DNA, because it exposes more functional groups that identify a base pair. However there are some known minor groove DNA-binding ligands such as Netropsin, Distamycin, Hoechst 33258, Pentamidine and others.
Read more about DNA-binding Protein: Examples, Non-specific DNA-protein Interactions, DNA-binding Proteins That Specifically Bind Single-stranded DNA, Binding To Particular DNA Sequences
Other articles related to "protein, proteins":
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... In contrast, other proteins have evolved to bind to particular DNA sequences ... The most intensively studied of these are the various transcription factors, which are proteins that regulate transcription ... either directly or through other mediator proteins this locates the polymerase at the promoter and allows it to begin transcription ...
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