Dbait

Some articles on dbait:

Si DNA - Mechanism of Action
... The siDNA family, lead by Dbait consists of 32 base pairs deoxyribonucleotide forming an intramolecular double helix, which mimicks DNA double-strand break lesions ... Dbait binds to and hyperactivate DNA-PK, an enzyme involved in DNA breaks signaling and repair ... Dbait-dependent unspecific phosphorylation of H2AX results in inefficient double strand break recognition and repair ...