|Molecular function||• protein serine/threonine phosphatase activity
• iron ion binding
• protein binding
• heme binding
• electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
|Cellular component||• protein phosphatase type 2A complex
• mitochondrial inner membrane
• mitochondrial intermembrane space
• respiratory chain
|Biological process||• apoptotic DNA fragmentation
• apoptotic process
• activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
• respiratory electron transport chain
• small molecule metabolic process
• cellular respiration
|Sources: Amigo / QuickGO|
25.16 – 25.16 Mb
24.88 – 24.88 Mb
The Cytochrome complex, or cyt c is a small heme protein found loosely associated with the inner membrane of the mitochondrion. It belongs to the cytochrome c family of proteins. Cytochrome c is a highly soluble protein, unlike other cytochromes, with a solubility of about 100 g/L and is an essential component of the electron transport chain, where it carries one electron. It is capable of undergoing oxidation and reduction, but does not bind oxygen. It transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase). In humans, cytochrome c is encoded by the CYCS gene.
Other articles related to "cytochrome c, cytochrome":
... Cytochrome c is widely believed to be localized solely in the mitochondrial intermembrane space under normal physiological conditions ... The release of cytochrome-c from mitochondria to the cytosol, where it activates the caspase family of proteases is believed to be primary trigger ... detailed immunoelectron microscopic studies with rat tissues sections employing cytochrome c-specific antibodies provide compelling evidence that cytochrome-c under normal cellular conditions is ...
... living organisms have it, because it performs very basic life functions) protein Cytochrome c in living cells ... The variance of cytochrome c of different organisms is measured in the number of differing amino acids, each differing amino acid being a result of a base pair ... by the estimated time it takes for a substituted base pair of the cytochrome c gene to be successfully passed on ...