2-Phenylcyclopentan-1-amine is a compound with two stereocenters. Thus, the following four following stereoisomers may exist:
The racemate (±)-trans-2-phenylcyclopentan-1-amine is the active ingredient of cypenamine. Furthermore, the kinetic resolution of (±)-trans-2-phenylcyclopentan-1-amine by lipase B from Candida antarctica may effectivily performed by an aminolysis reaction.
Racemic cis-2-phenylcyclopentan-1-amine has found no pharmacological application.
Read more about this topic: Cypenamine
Other articles related to "stereochemistry":
... The stereochemistry of the product 5 is due to the addition of the ylide 1 to the carbonyl 2 and to the ability of the intermediates to equilibrate ... For many years, the stereochemistry of the Wittig reaction, in terms of carbon-carbon bond formation, had been assumed to correspond directly with the Z/E stereochemistry of the alkene ...
... Wavy single bonds represent unknown or unspecified stereochemistry or a mixture of isomers ... continually opens and closes, sometimes closing with one stereochemistry and sometimes with the other ...
... It was logical, then, to consider the potential for improving the selectivity and potency of ibuprofen formulations by marketing ibuprofen as a single-enantiomer product (as occurs with naproxen, another NSAID) ... Further in vivo testing, however, revealed the existence of an isomerase (alpha-methylacyl-CoA racemase), which converted (R)-ibuprofen to the active (S)-enantiomer (R)-ibuprofen (S)-ibuprofen ...
... Postscript) Molfile PNG (with Pycairo installed) SMILES (Stereochemistry is not supported) InChI (with InChI program) Imports Molfile SMILES (Stereochemistry is not supported) InChI (Stereoc ...