Clamp Loader

Some articles on clamp loader, clamp, clamps, clamp loaders:

Replisome - Solving The Challenges of DNA Replication - Ensuring Processivity and Synchronisation - Clamp Loader
... Clamp loader is a generic term that refers to replication factors called gamma (prokaryotes) or RFC (eukaryotes) ... DNA and primer RNA is referred to as 'A-form DNA' and it is thought that clamp loading replication proteins (helical heteropentamers) want to associate with A-form DNA because of its ... Thus, clamp loading proteins associate with the primed region of the strand which causes hydrolysis of ATP and provides energy to open the clamp and attach it to the strand ...
DNA Clamp - Assembly
... Sliding clamps are loaded onto their associated DNA template strands by specialized proteins known as "sliding clamp loaders", which also disassemble the clamps after ... the binding sites for the DNA polymerase, so the clamp cannot simultaneously associate with a clamp loader and with a polymerase ... Thus the clamp will not be actively disassembled while the polymerase remains bound ...