CEBPA

CEBPA

Identifiers Symbols CEBPA; C/EBP-alpha; CEBP External IDs OMIM: 116897 MGI: 99480 HomoloGene: 3211 GeneCards: CEBPA Gene

Gene Ontology
Molecular function DNA binding
sequence-specific DNA binding transcription factor activity
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
protein binding
transcription factor binding
protein domain specific binding
protein complex binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
Cellular component nucleus
nuclear matrix
Rb-E2F complex
Biological process urea cycle
negative regulation of transcription from RNA polymerase II promoter
liver development
embryonic placenta development
generation of precursor metabolites and energy
transcription, DNA-dependent
transcription from RNA polymerase II promoter
acute-phase response
mitochondrion organization
cholesterol metabolic process
negative regulation of cell proliferation
virus-host interaction
cytokine-mediated signaling pathway
myeloid cell differentiation
macrophage differentiation
lung development
organ regeneration
response to vitamin B2
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase III promoter
cell maturation
inner ear development
white fat cell differentiation
brown fat cell differentiation
response to glucocorticoid stimulus
cellular response to lithium ion
cellular response to organic cyclic compound
Sources: Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1050 12606 Ensembl ENSG00000245848 ENSMUSG00000034957 UniProt P49715 P53566 RefSeq (mRNA) NM_004364 NM_007678 RefSeq (protein) NP_004355 NP_031704 Location (UCSC) Chr 19:
33.79 – 33.79 Mb Chr 7:
35.12 – 35.12 Mb PubMed search

CCAAT/enhancer-binding protein alpha is a protein that in humans is encoded by the CEBPA gene.

Read more about CEBPA:  Function, Interactions, Clinical Significance

Other articles related to "cebpa":

CEBPA - Clinical Significance
... It has been shown that mutation of CEBPA has been linked to good outcome in both adult and pediatric acute myeloid leukemia patients ...