Carbonyl Substituent

Some articles on carbonyl, substituents, substituent, carbonyl substituent, carbonyls:

Carbonyl 1,2 Asymmetric Induction - Anti–Felkin Selectivity
... preferential addition of a nucleophile to the most sterically favored face of a carbonyl moiety ... O, N, S, P substituents) ... This locks the carbonyl and the Lewis base substituent in an eclipsed conformation, and the nucleophile will then attack from the side with the smallest free α-carbon substituent ...
Carbonyl 1,2 Asymmetric Induction - Felkin Model
... the stereochemistry of nucleophilic addition reactions to carbonyl groups ... in the transition state between the carbonyl substituent (the hydrogen atom in aldehydes) and the largest α-carbonyl substituent ... He demonstrated that by increasing the steric bulk of the carbonyl substituent from methyl to ethyl to isopropyl to isobutyl, the stereoselectivity ...
Flippin–Lodge Angle
... center in a molecule, originally the carbonyl center in an organic ketone, but now extending to aldehyde, ester, and amide carbonyls, and to alkenes (olefins) as well ... In the example of nucleophilic attack at a carbonyl, the FL angle is a measure of the "offset" of the nucleophile's approach to the electrophile, toward one or the other of the two ... after projection of Nu onto the carbonyl plane and measuring the angle supplementary to LNu'-C-O (where Nu' is the projected atom) ...