Carbetocin - Interactions With Other Drugs and Neurotransmitter Systems

Interactions With Other Drugs and Neurotransmitter Systems

Due to oxytocin’s close sequence homology with vasopressin, oxytocin analogs often bind with much lower affinity to vasopressin receptors V1, in the uterine lining, and V2, in the kidneys and may consequently interact with or disrupt the vasopressin circuitry and feedback loops.

Carbetocin may work synergistically with drugs such as Dinoprostone and Misoprostol that ripen the cervix. Concurrent use of these drugs can be risky, particularly during pregnancy and prenatal care, possibly causing premature labor or abortion.

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