Comparison With Other Drugs
Due to carbetocin's considerably longer half-life, its effects are longer lasting than other oxytocin homologs such as Pitocin or Barusiban. A single carbetocin administration compared to a placebo or an eight hour intravenous drip of oxytocin in a randomized blind study, necessitated significantly less additional oxytocin therapy following a Cesarean section. Oxytocin receptor antagonists, such as Barusiban or Atosiban have the opposite effect of depressing oxytocin receptor activity and can be used to stop premature labor and uterine contractions.
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