Candesartan (rINN) ( /ˌkændɨˈsɑrtən/) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. The prodrug candesartan cilexetil is marketed by AstraZeneca and Takeda Pharmaceuticals, commonly under the trade names Blopress, Atacand, Amias, and Ratacand.

Read more about CandesartanClinical Use, Chemistry and Pharmacology

Other articles related to "candesartan":

Amias - Chemistry and Pharmacology
... Candesartan is marketed as the cyclohexyl 1-hydroxyethyl carbonate (cilexetil) ester, known as candesartan cilexetil ... Candesartan cilexetil is metabolised completely by esterases in the intestinal wall during absorption to the active candesartan moieity ... The use of a prodrug form increases the bioavailability of candesartan ...
Angiotensin II Receptor Antagonist - Medical Uses
... failure in patients intolerant of ACE inhibitor therapy, particularly candesartan ... Candesartan is used experimentally in preventive treatment of migraine ... Lisinopril has been found less often effective than candesartan at preventing migraine ...
Discovery And Development Of Angiotensin Receptor Blockers - Drug Comparison and Pharmacokinetics
... Daily dosage Losartan 2 98.7 33 10/90 Minimal 50-100 EXP 3174 6-9 99.8 - 50/50 - - Candesartan 9 >99 15 60/40 No 4-32 Valsartan 25. 30/70 40-50% decreased by 80-320 Irbesartan 11-15 90-95 70 1/99 ... As mentioned before, candesartan cilexetil and olmesartan medoxomil are inactive ester prodrugs that are completely hydrolyzed to their active forms by ... for the metabolizing of losartan to EXP 3174 and the slow metabolizing of valsartan and candesartan to their inactive metabolites ...