A cancer syndrome is a genetic disorder in which genetic mutations in one or more genes predispose the affected individuals to the development of cancers and may also cause the early onset of these cancers. Cancer syndromes often show not only a high lifetime risk of developing cancer, but also the development of multiple independent primary tumors. Many of these syndromes are caused by mutations in tumor suppressor genes, genes that are involved in protecting the cell from turning cancerous. Other genes that may be affected are DNA repair genes and oncogenes. Common examples of inherited cancer syndromes are Hereditary breast-ovarian cancer syndrome and Hereditary non-polyposis colon cancer (Lynch syndrome).
Other articles related to "cancer syndrome, cancer, syndrome, cancers":
... Hereditary non-polyposis colon cancer (HNPCC), also known as Lynch syndrome, is an autosomal dominant cancer syndrome that increases the risk of colorectal cancer ... In addition to colorectal cancer many other cancers are increased in frequency ... These include endometrial cancer, stomach cancer, ovarian cancer, cancers of the small bowel and pancreatic cancer ...
Famous quotes containing the words syndrome and/or cancer:
“[T]he syndrome known as life is too diffuse to admit of palliation. For every symptom that is eased, another is made worse. The horse leechs daughter is a closed system. Her quantum of wantum cannot vary.”
—Samuel Beckett (19061989)
“We need cancer because, by the very fact of its incurability, it makes all other diseases, however virulent, not cancer.”
—Gilbert Adair, British author, critic. Under the Sign of Cancer, Myths and Memories (1986)