Azlocillin

Azlocillin is an acylampicillin antibiotic with an extended spectrum of activity and greater in vitro potency than the carboxy penicillins. Azlocillin is similar to mezlocillin and piperacillin. It demonstrates antibacterial activity against a broad spectrum of bacteria, including Pseudomonas aeruginosa and, in contrast to most cephalosporins, exhibits activity against enterococci.

Antibacterials: cell envelope antibiotics (J01C-J01D)
Intracellular
  • inhibit peptidoglycan subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
  • DADAL/AR inhibitors (Cycloserine)
  • bactoprenol inhibitors (Bacitracin)
Glycopeptide
  • inhibit PG chain elongation: Vancomycin# (Oritavancin
  • Telavancin)
  • Teicoplanin (Dalbavancin)
  • Ramoplanin
β-lactams/
(inhibit PBP
cross-links)
Penicillins
(penams)
Extended sp.
  • aminopenicillins: Amoxicillin#
  • Ampicillin# (Pivampicillin
  • Hetacillin
  • Bacampicillin
  • Metampicillin
  • Talampicillin)
  • Epicillin
  • carboxypenicillins: Carbenicillin (Carindacillin)
  • Ticarcillin
  • Temocillin
  • ureidopenicillins: Azlocillin
  • Piperacillin
  • Mezlocillin
  • other: Mecillinam (Pivmecillinam)
  • Sulbenicillin
Narrow sp.
β-lactamase sensitive
  • Benzylpenicillin (G)#: Clometocillin
  • Benzathine benzylpenicillin#
  • Procaine benzylpenicillin#
  • Azidocillin
  • Penamecillin
  • Phenoxymethylpenicillin (V)#: Propicillin
  • Benzathine phenoxymethylpenicillin
  • Pheneticillin
β-lactamase resistant
  • Cloxacillin# (Dicloxacillin
  • Flucloxacillin)
  • Oxacillin
  • Meticillin
  • Nafcillin
Penems
  • Faropenem
Carbapenems
  • Biapenem
  • Ertapenem
  • antipseudomonal (Doripenem
  • Imipenem
  • Meropenem)
  • Panipenem
Cephalosporins/Cephamycins
(cephems)
1st (PEcK)
  • Cefazolin#
  • Cefacetrile
  • Cefadroxil
  • Cefalexin
  • Cefaloglycin
  • Cefalonium
  • Cefaloridine
  • Cefalotin
  • Cefapirin
  • Cefatrizine
  • Cefazedone
  • Cefazaflur
  • Cefradine
  • Cefroxadine
  • Ceftezole
2nd (HEN)
  • Cefaclor
  • Cefamandole
  • Cefminox
  • Cefonicid
  • Ceforanide
  • Cefotiam
  • Cefprozil
  • Cefbuperazone
  • Cefuroxime
  • Cefuzonam
  • cephamycin (Cefoxitin
  • Cefotetan
  • Cefmetazole)
  • carbacephem (Loracarbef)
3rd
  • Cefixime#
  • Ceftriaxone#
  • antipseudomonal (Ceftazidime#
  • Cefoperazone)
  • Cefcapene
  • Cefdaloxime
  • Cefdinir
  • Cefditoren
  • Cefetamet
  • Cefmenoxime
  • Cefodizime
  • Cefotaxime
  • Cefpimizole
  • Cefpiramide
  • Cefpodoxime
  • Cefsulodin
  • Cefteram
  • Ceftibuten
  • Ceftiolene
  • Ceftizoxime
  • oxacephem (Flomoxef
  • Latamoxef ‡)
4th (antips-)
  • Cefepime
  • Cefozopran
  • Cefpirome
  • Cefquinome
5th
  • Ceftobiprole
  • Ceftaroline fosamil
Veterinary
  • Ceftiofur
  • Cefquinome
  • Cefovecin
Monobactams
  • Aztreonam
  • Tigemonam
  • Carumonam
  • Nocardicin A
β-lactamase inh.
  • penam (Sulbactam
  • Tazobactam)
  • clavam (Clavulanic acid)
Combinations
  • Amoxicillin/clavulanic acid#
  • Imipenem/cilastatin#
  • Ampicillin/flucloxacillin
  • Ampicillin/sulbactam (Sultamicillin)
  • Piperacillin/tazobactam
Other
  • polymyxins/detergent (Colistin
  • Polymyxin B)
  • depolarizing (Daptomycin)
  • hydrolyze NAM-NAG (Lysozyme)
  • Gramicidin
  • #WHO-EM
  • ‡Withdrawn from market
  • Clinical trials:
    • †Phase III
    • §Never to phase III

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)