Artefill is a non-resorbable injectable dermal filler for the correction of wrinkles and lines on the face. Artefill is approved by the U.S. Food and Drug Administration (FDA) for correctıng smile lines (nasolabial folds) but it is widely used "off label" by physicıans to fill lines and wrinkles all over the face. It is a formulation of medical grade polymethylmethacrylate (PMMA) microspheres and bovine collagen along with lidocaine and buffers. The PMMA microspheres in Artefill are not absorbed by the body and therefore provide permanent support for wrinkle correction.
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