Antimicrobial Peptides

Antimicrobial peptides (also called host defense peptides) are an evolutionarily conserved component of the innate immune response and are found among all classes of life. Fundamental differences exist between prokaryotic and eukaryotic cells that may represent targets for antimicrobial peptides. These peptides are potent, broad spectrum antibiotics which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria (including strains that are resistant to conventional antibiotics), mycobacteria (including Mycobacterium tuberculosis), enveloped viruses, fungi and even transformed or cancerous cells. Unlike the majority of conventional antibiotics it appears as though antimicrobial peptides may also have the ability to enhance immunity by functioning as immunomodulators.

Read more about Antimicrobial Peptides:  Structure, Activities, Immunomodulation, Mode of Action, Therapeutic Potential, Selectivity, Bacterial Resistance, Examples, Bioinformatics

Other articles related to "antimicrobial peptides, peptides, antimicrobial, antimicrobial peptide":

Skin Flora - Skin Defenses - Antimicrobial Peptides
... The skin creates antimicrobial peptides such as cathelicidins that control the proliferation of skin microbes ... Psoriasis has been linked to self-DNA created from cathelicidin peptides that causes autoinflammation ...
Peripheral Membrane Protein - Categories of Peripheral Proteins - Polypeptide Hormones, Toxins, and Antimicrobial Peptides
... Many hormones, toxins, inhibitors, or antimicrobial peptides interact specifically with transmembrane protein complexes ... Some water-soluble proteins and peptides can also form transmembrane channels ... although some of the channel-forming peptides are rather hydrophobic and therefore were studied by NMR spectroscopy in organic solvents or in the presence of micelles ...
Magainin
... Magainin are a class of antimicrobial peptides found in the African clawed frog Xenopus laevis ... He hypothesized that some form of antimicrobial agent was being expressed on the skin ... Within several months these agents were isolated, chemically identified as peptides, and synthesized in the laboratory ...
Antimicrobial Peptides - Bioinformatics
... databases exist to catalogue antimicrobial peptides such as CAMP, the Antimicrobial Peptide Database (http//aps.unmc.edu/AP/main.php) and BioPD (http//biopd.bjmu.edu.cn/help.asp) ...