Alzheimer's Disease Clinical Research - Treatments in Clinical Development - Other - Antibiotic Therapy

Antibiotic Therapy

Only one clinical trial is being done (at McMaster University) to investigate the efficacy of antibiotic therapy. The authors of the study indicated that it was effective in delaying the progress of the disease: "In conclusion, a 3-month course of doxycycline and rifampin reduced cognitive worsening at 6 months of follow-up in patients with mild to moderate AD." A re-examination of the same data using: "...AUC analysis of the pooled index showed significant treatment effect over the 12-month period".

Several studies using minocycline and doxycycline, in an animal model of Alzheimer's Disease, have indicated that minocycline and doxycycline exerts a protective effect in preventing neuron death and slowing the onset of the disease.

Read more about this topic:  Alzheimer's Disease Clinical Research, Treatments in Clinical Development, Other

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