Acetaldehyde Dehydrogenase

Acetaldehyde Dehydrogenase

Acetaldehyde dehydrogenases (EC 1.2.1.10) are dehydrogenase enzymes which catalyze the conversion of acetaldehyde into acetic acid. The oxidation of acetaldehyde to acetate can be summarized as follows:

CH3CHO + NAD+ + CoA → acetyl-CoA + NADH + H+

In humans, there are three known genes which encode this enzymatic activity, ALDH1A1, ALDH2, and the more recently discovered ALDH1B1 (also known as ALDH5). These enzymes are members of the larger class of aldehyde dehydrogenases.

The CAS number for this type of the enzyme is .

Read more about Acetaldehyde Dehydrogenase:  Structure, Evolution, Role in Metabolism of Alcohol

Other articles related to "acetaldehyde dehydrogenase, dehydrogenase, acetaldehyde":

Acetaldehyde Dehydrogenase - Role in Metabolism of Alcohol
... In the liver, the enzyme alcohol dehydrogenase oxidizes ethanol into acetaldehyde, which is then further converted into the harmless acetic acid (vinegar) by ... Acetaldehyde is more toxic than alcohol and is responsible for many hangover symptoms ... N-acetylcysteine (NAC) is known to assist in processing acetaldehyde in the body and therefore can help to relieve hangover symptoms ...